Teaching neuroimages: posttraumatic neuroma-in-continuity of the right tibial nerve.

The Healing Effect of Silicone Gel on Sciatic Nerve Injuries in Experimental Rat

BACKGROUND Peripheral nerve repair is often complicated by fibroblastic scar formation, nerve dysfunction, and traumatic neuroma formation. Use of silicone may improve outcomes of these repairs. In this study, we tried to evaluate effectiveness of silicone gel on rats’ sciatic nerve repair, axon regeneration and scar formation around and in the nervous tissues. METHODS This experimental stud...

Teaching NeuroImages: intraneural ganglion cyst of the tibial nerve.

A 59-year-old man with knee arthritis suddenly developed left posterior thigh pain and complete paralysis of his foot. EMG/nerve conduction studies localized the lesion to the distal sciatic nerve in the thigh (absent motor units from the short head of biceps femoris but normal vastus lateralis). Imaging demonstrated an intraneural ganglion cyst in the tibial nerve extending up to the sciatic n...

Effect of Dexamethasone on Preventing Tibial Nerve Conduction Velocity Loss in Tourniquet Neurepathic Rat

Introduction: Ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. As dexamethasone (Dex) has been shown to Prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. Methods: 36 male Wistar rats (200-250 gr) were chosen and divided randomly into 6 equal grou...

The Impact of Motor Axon Misdirection and Attrition on Behavioral Deficit Following Experimental Nerve Injuries

Peripheral nerve transection and neuroma-in-continuity injuries are associated with permanent functional deficits, often despite successful end-organ reinnervation. Axonal misdirection with non-specific reinnervation, frustrated regeneration and axonal attrition are believed to be among the anatomical substrates that underlie the poor functional recovery associated with these devastating injuri...

Cystic Neuroma of the Posterior Tibial Nerve